With increasingly demand for inexpensive residence DNA testing, the sphere of accessible checks retains rising. Some supply extra specialised outcomes or the power to buy solely the testing classes you need, whereas others would possibly undercut the bigger-name kits on value.
TellMeGen claims to supply the whole bundle, with each well being/medical testing and ancestry outcomes at a single buy value. Nevertheless, in observe, the service is clearly targeted way more on the previous than the latter, offering a protracted record of well being traits and medical circumstances with ample element… after which barely scratching the floor with its simplistic ancestry outcomes.
Notice: This evaluate is a part of our greatest DNA take a look at equipment roundup. Go there for particulars about competing merchandise and the way we examined them.
You’ll have to mail in a saliva pattern for TellMeGen to investigate your DNA. Right here’s what’s within the equipment:
- Saliva assortment tube with DNA stabilizing resolution
- Funnel high
- Plastic clamshell casing
- Pay as you go return label
Gathering a sizable-enough pattern for TellMeGen means spitting into the included plastic tube over and over till you fill it to the road (not together with bubbles). It took me just a few stable minutes of conjuring up fluids to satisfy the quota, however at the least it’s an easy request.
Having to unscrew the cap, screw on the funnel cap, after which unscrew the funnel and exchange the unique cap earlier than mailing provides further potential for fumbling the tube and doubtlessly shedding the free-floating stabilizing resolution—so watch out with it. It’s not as intelligent as 23andMe’s tube, which has its resolution sealed within the funnel cap and releases it into your saliva pattern whenever you securely shut it.
TellMeGen estimates that outcomes might be out there inside 4 to 6 weeks of receiving the pattern. I registered an account and my equipment when making ready the pattern, however didn’t obtain any sort of electronic mail alert that my outcomes had been out there. 5 weeks after sending the pattern, I logged into my account and located that the equipment truly was not tied to the account, regardless of finishing that step throughout preliminary registration.
Fortunately, after I registered the equipment once more, the outcomes had been already out there. Sadly, I don’t know precisely how lengthy it took because of the equipment registration mishap, however the turnaround nonetheless fell throughout the estimated window. Comparatively, I despatched 23andMe and AncestryDNA samples again on the identical time, and acquired outcomes from each providers in simply over two weeks.
TellMeGen is an autosomal DNA take a look at, very similar to 23andMe, AncestryDNA, and different well-liked checks, which analyzes the 22 pairs of autosomal chromosomes moreover the X and Y intercourse chromosomes. In accordance with the corporate, it might probably analyze greater than 655,000 single nucleotide polymorphisms (SNPs)—or DNA sequence variations—used to trace organic variations in addition to shared connections to family members.
Ancestry is listed final underneath the “My Outcomes” part on the TellMeGen web site, and that may be a sign of its significance on this explicit DNA take a look at. The ancestry outcomes are extremely simplistic, sadly, with little in the way in which of interactivity or depth.
In my case, the outcomes confirmed that I’m 89 p.c British; almost 9 p.c Russian: Adyghe individuals; and about 2 p.c French: Basque. Each 23andMe and AncestryDNA likewise pointed to almost 100 p.c Northwestern European totals, however neither estimated that the overwhelming majority of that was British. Actually, each of these checks demonstrated much more nuance of their estimations of my ancestors’ origins.
The proportion estimates are proven in a chart atop a map, however you may’t actually do something on the map besides click on on the highlighted nations. Flip over to the Particulars tab and also you’ll discover a bit of extra info on every area—emphasis on “little.” Every clarification for my highlighted areas had simply two to a few sentences of data.
It actually pales compared to the aforementioned rival providers. Click on on 23andMe’s outcomes and also you’ll get exhaustive explanations of every area, an interactive map with latest ancestry information, a number of further background element and pictures, and hyperlinks to discover extra in regards to the area. It’s a world of distinction. TellMeGen has almost nothing price digging into. It’s very disappointing.
TellMeGen additionally has no matching service for connecting with individuals with related DNA. So when it comes to studying extra about the place your ancestors got here from or discovering long-lost kin, you’re higher served by one other service akin to 23andMe or AncestryDNA.
In accordance with TellMeGen, its ancestry information is especially from Western Europe (Iberian and Central European), with sources together with public databases such because the Human Genome Range Venture. TellMeGen analyzes greater than 12,500 SNPs to detect international populations, and plans to repeatedly replace its information. New populations and subpopulations might be added in September, with the opportunity of different options—akin to relative-matching—into account.
Fortunately, TellMeGen offers a good bit extra info in its health-related outcomes, that are cut up into three classes: Advanced Ailments, Inherited Circumstances, and Traits. Beneath Advanced Ailments, TellMeGen exhibits an inventory of circumstances cut up between high-risk, low-risk, and typical-risk classes, along with your threat proportion proven in comparison with the typical.
For instance, it says that I’m almost 14 occasions extra prone to develop stressed leg syndrome than the remainder of the inhabitants. Fortunately, that hasn’t occurred to me—but, at the least. However I can click on on the itemizing and browse extra about what it’s, the signs, the genetic function, and my very own technical report, which highlights every SNP tracked, the genotype the take a look at returned, and what that end result means. It additionally offers additional element for every SNP, together with a bibliography for anybody searching for additional context.
The opposite classes are equally detailed, however the web site lacks the polish and imagery of one thing like 23andMe, for instance. That stated, TellMeGen gives an extended record of traits and well being circumstances that it take a look at for than the 23andMe Well being + Ancestry take a look at, however the outcomes are typically ambiguous. At occasions, it merely pointed me in the direction of my technical report, which then typically gave conflicting information based mostly on which SNP was examined. In some instances, the entire examined SNPs had been in settlement, but TellMeGen nonetheless didn’t present a conclusive end result.
Each TellMeGen and the 23andMe Well being + Ancestry take a look at delivered related outcomes concerning sure traits, akin to seemingly elevated caffeine consumption and unlikeliness to have an alcohol flush response. Whereas TellMeGen’s lists are longer, nonetheless, 23andMe’s measured traits are total extra enjoyable and fascinating (like “Potential to Match Musical Pitch” and “Toe Size Ratio”), plus 23andMe does a a lot, a lot better job of presenting its outcomes than TellMeGen. You’ll usually get a plain wall of textual content with TellMeGen, whereas 23andMe has bespoke graphics all over the place, together with charts and graphs, and simply digestible chunks of information and information.
If you register a equipment, you’ll need to comply with the knowledgeable consent settlement to proceed. The doc states that you simply agree to permit TellMeGen to obtain and analyze your DNA, and supply the outcomes—even when these outcomes show to “trigger conditions of emotional stress.” You too can select whether or not to permit your information for use anonymously for analysis. That’s your name to make.
Your equipment has a 12-character alphanumeric code hooked up to it, and the laboratory that analyzes the equipment is not going to have entry to your figuring out info, together with your full identify. Moreover, all bodily samples are routinely destroyed two months following completion of testing. That’s useful, because it signifies that you wouldn’t have to contact customer support to have a pattern destroyed, in contrast to with another providers.
TellMeGen retains issues easy with its pricing method, promoting a single equipment for $169 by way of its web site. There’s no add-on service or separate variations focused towards several types of outcomes: It’s one buy for the total set of outcomes. That’s cheaper than 23andMe’s Well being + Ancestry take a look at, which is $199, however there’s an enormous distinction within the expertise given TellMeGen’s barebones web site and experiences.
As talked about, TellMeGen is considerably extra targeted on the well being facet of the DNA testing equation, with the ancestry part coming off as a really minor add-on. Hopefully the ancestry part of the service might be additional enhanced over time and customers’ outcomes might be up to date with additional element and nuance. Proper now, it’s not a lot of a promoting level, however the well being outcomes are wide-ranging and fascinating.
Editor’s observe: As a result of on-line providers are sometimes iterative, gaining new options and efficiency enhancements over time, this evaluate is topic to alter so as to precisely mirror the present state of the service. Any modifications to textual content or our closing evaluate verdict might be famous on the high of this text.
This story, “TellMeGen evaluate: Heavy on DNA-driven well being outcomes, however gentle on ancestry ” was initially revealed by